Cartilage Tissue Engineering Using Cryogenic Chondrocytes
نویسندگان
چکیده
منابع مشابه
Cartilage tissue engineering using cryogenic chondrocytes.
OBJECTIVE To generate in vitro hyaline cartilage from cryogenically preserved human septal chondrocytes in a simulated microgravity environment on a 3-dimensional biodegradable scaffolding material. METHODS In this experiment, cryogenically frozen chondrocytes were thawed and cultured in a monolayer in serum-based chondrocyte media. They were seeded onto 3-dimensional biopolymer scaffolds in ...
متن کاملTissue engineering: chondrocytes and cartilage
Tissue engineering offers new strategies for developing treatments for the repair and regeneration of damaged and diseased tissues. These treatments, using living cells, will exploit new developments in understanding the principles in cell biology that control and direct cell function. Arthritic diseases that affect so many people and have a major impact on the quality of life provide an import...
متن کاملHigh Quality of Infant Chondrocytes in Comparison with Adult Chondrocytes for Cartilage Tissue Engineering
BACKGROUND Tissue engineering is used for the treatment of many diseases, and the ideal cell source for cartilage tissue engineering is chondrocytes. The main limitation of chondrocyte is the low number of cells in cartilage tissue engineering. This study investigated a suitable cell source with high proliferation rate to obtain a large number of chondrocytes. METHODS Adult cartilage t...
متن کاملCartilage tissue engineering using pre-aggregated human articular chondrocytes.
In this study, we first aimed at determining whether human articular chondrocytes (HAC) proliferate in aggregates in the presence of strong chondrocyte mitogens. We then investigated if the aggregated cells have an enhanced chondrogenic capacity as compared to cells cultured in monolayer. HAC from four donors were cultured in tissue culture dishes either untreated or coated with 1% agarose in t...
متن کاملhigh quality of infant chondrocytes in comparison with adult chondrocytes for cartilage tissue engineering
background tissue engineering is used for the treatment of many diseases, and the ideal cell source for cartilage tissue engineering is chondrocytes. the main limitation of chondrocyte is the low number of cells in cartilage tissue engineering. this study investigated a suitable cell source with high proliferation rate to obtain a large number of chondrocytes. methods adult cartilage tissue sam...
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ژورنال
عنوان ژورنال: Archives of Otolaryngology–Head & Neck Surgery
سال: 2003
ISSN: 0886-4470
DOI: 10.1001/archotol.129.8.889